Download Ebook Phytochemical and Biological Investigations of Thunbergia Grandiflora PDF/Epub by Aszadur Rahman Chowdhury for free
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The author of the book: Aszadur Rahman Chowdhury
Edition: LAP Lambert Academic Publishing
Date of issue: 17 Jan 2012
Format files: Epub, PDF
The size of the: 428 KB
City - Country: Germany
Full description of the book "Phytochemical and Biological Investigations of Thunbergia Grandiflora":Thunbergia grandiflora(Acanthaceae) has been investigated for isolation of its secondary metabolites and evaluation of biological activities of the crude extractive. One compound had been isolated, which was identified by extensive analyses of resolution NMR spectral data. The powdered leaf of T. grandiflora was extracted separately with methanol. The solid extract was then subjected to vacuum liquid chromatography (VLC). Repeated chromatographic separation and purification the leaves of Thunbergia grandiflora afforded one flavonoid named 5 hydroxy-4',6,7- trimethoxy flavone, C18H16O6. The Methanolic crude extract of Thunbergia grandiflora showed moderate analgesic activity. Out of all the samples only chloroform fraction methanolic crude extract were PDF appeared mild potent in terms of both zone of inhibition & spectrum of activity against some gram positive, gram negative bacteria and fungi. In antidiarrhoeal test and brine shrimp lethality bioassay, hexane, carbon tetrachloride, chloroform and aqueous fractions exhibited insignificant activities whereas Carbon tetra chloride fraction showed some hypoglycemic effect at a dose of 300 mg/kg body weight compared to control group.
About the author Aszadur Rahman ChowdhuryAszadur Rahman Chowdhury has completed MPharm in Clinical Pharmacy and Pharmacology from faculty of pharmacy, University of Dhaka. Now, he is working in SQUARE pharmaceuticals Ltd. K. M. Shams-Ud-Doha and Kh. Tanvir Ahmed is working as Lecturer, Department of Pharmacy, East West University.They are Self-motivated, energetic and enthusiastic.
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